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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KDM6B
All Species:
9.09
Human Site:
Y422
Identified Species:
20
UniProt:
O15054
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15054
NP_001073893
1679
180411
Y422
G
I
P
G
A
D
H
Y
Q
T
P
A
L
E
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110616
1677
180308
Y421
G
I
P
G
A
D
H
Y
Q
T
P
A
L
E
V
Dog
Lupus familis
XP_546599
1653
177377
Q431
I
P
G
A
D
H
Y
Q
T
P
A
L
D
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5NCY0
1641
176337
Q429
I
P
G
A
D
H
Y
Q
N
P
A
L
E
I
S
Rat
Rattus norvegicus
NP_001102299
1361
146305
E228
E
D
G
E
I
L
G
E
L
F
F
G
A
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512545
1373
151321
S240
G
D
K
A
T
K
E
S
Y
A
I
Q
Y
L
Q
Chicken
Gallus gallus
XP_416762
1384
152840
Y251
D
K
A
T
K
E
S
Y
A
I
Q
Y
L
Q
K
Frog
Xenopus laevis
NP_001086774
1455
160368
T322
K
S
E
A
S
A
D
T
W
C
S
I
G
V
L
Zebra Danio
Brachydanio rerio
XP_684619
1964
216217
S431
S
Q
I
A
A
R
H
S
Q
A
H
N
S
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_723550
939
106399
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203582
1412
156309
S279
G
Q
P
N
S
T
P
S
S
Q
A
Q
V
N
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98
91.7
N.A.
90.1
74.6
N.A.
31.8
31.6
31
39.5
N.A.
27.6
N.A.
N.A.
29.6
Protein Similarity:
100
N.A.
98.4
93
N.A.
92.2
76.2
N.A.
44.3
44.7
45
51
N.A.
39.4
N.A.
N.A.
43.7
P-Site Identity:
100
N.A.
100
0
N.A.
0
6.6
N.A.
6.6
13.3
0
26.6
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
100
6.6
N.A.
6.6
6.6
N.A.
6.6
26.6
13.3
26.6
N.A.
0
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
46
28
10
0
0
10
19
28
19
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
10
19
0
0
19
19
10
0
0
0
0
0
10
0
0
% D
% Glu:
10
0
10
10
0
10
10
10
0
0
0
0
10
28
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% F
% Gly:
37
0
28
19
0
0
10
0
0
0
0
10
10
0
10
% G
% His:
0
0
0
0
0
19
28
0
0
0
10
0
0
0
0
% H
% Ile:
19
19
10
0
10
0
0
0
0
10
10
10
0
19
0
% I
% Lys:
10
10
10
0
10
10
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
0
0
0
0
10
0
0
10
0
0
19
28
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
10
0
0
10
0
10
0
% N
% Pro:
0
19
28
0
0
0
10
0
0
19
19
0
0
0
0
% P
% Gln:
0
19
0
0
0
0
0
19
28
10
10
19
0
10
10
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
0
0
19
0
10
28
10
0
10
0
10
0
19
% S
% Thr:
0
0
0
10
10
10
0
10
10
19
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
10
19
28
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
19
28
10
0
0
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _